Agency for Healthcare Research and Quality (AHRQ): The Agency for Healthcare Research and Quality (AHRQ) was established to fund and conduct research aimed at improving the quality of healthcare. Additionally, AHRQ is tasked with disseminating this evidence and translating it into clinical practice.
Centers for Disease Control and Prevention (CDC): Tasked with protecting the nation from health, safety and security threats, both foreign and in the U.S. Monitors reported disease and maintains information databases on prevalence, region, etc.
Centers for Medicare and Medicaid Services (CMS): Administers healthcare/ reimbursement programs including Medicare, Medicaid, and the Children’s Health Insurance Program (CHIP).
- Medicaid: An entitlement program administered between the federal government and state governments that provides health insurance for adults and children with limited income and resources, pregnant women, and qualifying children with complex medical conditions
- Medicare: a federal system of health insurance for people over 65 years of age or for certain younger people with disabilities
Department of Defense (CDMRP): The Department of Defense hosts the Congressionally Directed Medical Research Programs. CDMRP was created in 1992 via a Congressional appropriation to foster novel approaches to biomedical research in response to the expressed needs of its stakeholders. Stakeholders include the America public, the military and Congress.
Department of Education: The department of the U.S federal government that administers federal programs related to education.
Department of Health and Human Services (HHS): A cabinet-level department of the U.S. federal government with the goal of protecting the health of all Americans and providing essential human Services. This Department includes the below agencies, among others (12 total).
Food and Drug Administration (FDA): Responsible for protecting the public health by ensuring the safety, efficacy, and security of human and veterinary drugs, biological products, and medical devices; and ensuring the safety of our nation’s food supply, cosmetics, and products that emit radiation.
- CDER: As part of the FDA, CDER, or Center for Drug Evaluation and Research, regulates over the counter and prescription drugs, including biological therapeutics and generic drugs.
- CBER: As part of the FDA, CBER, or Center for Biologics Evolution and Research, regulated biological products for human use under applicable federal laws.
- CDRH: As part of the FDA, CHRH, or Center for Devices and Radiological Health, is responsible for the premarket approval of all medical devices, as well as overseeing the manufacturing, performance and safety of these devices.
- OOPD: As part of the FDA, OOPD, or the Office of Orphan Products Development, evaluates information from product sponsors to determine if drugs, biologics or medical devices meet the criteria for certain incentives and administers grants to provide funding for research on rare diseases. The office also works on rare disease issues with medical and research communities, professional organizations, academia, government agencies, industry and rare disease patient groups.
Health Resources and Research Administration (HRSA): The primary federal agency for improving access to health care services for people who are uninsured, isolated or medically vulnerable. This agency administers several newborn screening programs.
National Institutes of Health (NIH): The nation’s medical research agency tasked with making discoveries that improve health and save lives. Comprised of 27 institutes and centers.
- National Center for Advancing Translations Sciences (NCATS): As part of the NIH, NCATS speeds the development of new rare disease treatments by focusing on scientific approaches that can address more than one disease at a time. NCATS has contributed to 55 Investigational New Drugs and 14 approved therapies.
Social Security Administration (SSA): An independent agency of the U.S. federal government that administers Social Security, a social insurance program consisting of retirement, disability, and survivor benefits.
Non-Government
Institute for Clinical and Economic Review (ICER): The Institute for Clinical and Economic Review (ICER) is an independent, non-partisan organization that has developed a framework for evidenced-based value assessments of new health technologies.
Patient-Centered Outcomes Research Institute (PCORI): The Patient-Centered Outcomes Research Institute (PCORI) is a non-profit, government-sponsored institute. PCORI funds effectiveness research with the goal of improving outcomes by equipping patients and caregivers with the information and data they need to make informed decisions. Funding for this institute has been approved through 2029.
